产品货号：
Z14086
中文名称：
DNMT1抗体
英文名称：
Anti-DNMT1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DNMT1 Antibody |
| 指标别名 | AIM;CXXC9;DNA MTase HsaI;DNMT;DNMT1;MCMT |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,ICC/IF,FCM,ELISA |
| 基因名称 | DNMT1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Dnmt1 recombinant protein (Position:D22-N126). |
| 实际分子量 | 183KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene.This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA.This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA.Methylation of DNA is an important component of mammalian epigenetic gene regulation.Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities.Variation in this gene has been associated with cerebellar ataxia,deafness,and narcolepsy,and neuropathy,hereditary sensory,type IE.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | P26358 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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